About the lab
Specialised cells in the brain monitor the body's nutritional and metabolic status, i.e. how much energy and nutrients we have available. When these cells work properly, they control appetite and metabolism to maintain energy homeostasis: produce hunger when energy levels are low, or satiety when they're high. Obesity occurs when these cells stop working properly.
The Blouet Lab employs a multi-disciplinary approach to characterise metabolic-sensing cells, perform discrete molecular manipulations of these cells and downstream neurocircuits, and use cutting-edge molecular genetics and refined functional assessments in behaving rodents to characterise how nutrients are detected by the brain to maintain energy homeostasis in health and disease.